Oswaldo Cruz's birthplace, Historical house in São Luiz do Paraitinga, Brazil.

Oswaldo Cruz's birthplace is a two-story building in São Luiz do Paraitinga constructed with traditional methods including rammed earth walls and ceramic tile roofing. The interior shows wattle and daub walls with a distinctive ceiling design featuring alternating wooden board patterns.

Oswaldo Cruz lived in this house until the age of five; in 1877 the family moved to Rio de Janeiro. The building later housed a health centre, a culture centre and a library, and was restored and reopened on 15 September 2014. It is listed by IPHAN and by Condephaat.

The house is named for Oswaldo Cruz, born here in 1872 and living here until age five, when his family moved to Rio de Janeiro in 1877. Over time the building has housed a health centre, a culture centre and a library, and it reopened on 15 September 2014 after restoration work.

The house is easily reached on foot from central São Luiz do Paraitinga and sits within the historic old town. Visitors should allow time to explore the exhibitions and room layouts at a comfortable pace.

The house later served as a health centre, a cultural centre and a library before a restoration project; it was reopened on 15 September 2014. It stands at Rua Oswaldo Cruz no. 4 and is listed by both Iphan and Condephaat.