Silvermine Nature Reserve, Nature reserve in Western Cape, South Africa.

Silvermine Nature Reserve is part of Table Mountain National Park in Cape Town, South Africa, covering the Cape Peninsula range from the Kalk Bay mountains to Constantiaberg. The Ou Kaapse Weg main road runs through the reserve, cutting it into a northern and southern section. The Silvermine reservoir, built in 1898 to supply Cape Town with water, lies on the north side.

A dam was built here in the late 1800s to supply water to the nearby city. From the early 1900s onward, the area became a popular destination for walkers and people seeking open land close to Cape Town.

The reserve takes its name from the Silvermine River, which rises inside it and flows to Clovelly without crossing built-up land. The South African Navy's Maritime Rescue Co-ordination Centre sits in an underground bunker on the lower slopes of Silvermine mountain, opened with a maritime communications headquarters in 1973. A former signals station here was built in 1969 and used for the ECHELON interception project, covering a large part of the Indian and Atlantic Oceans.

The area is best explored on foot, with trails that range from short walks to longer hikes of several hours. Starting early in the morning is a good idea, as the light is softer and the heat less intense.

The river running through the reserve is one of the very few on the Cape Peninsula that does not pass through any developed land. This makes it one of the rare places where a completely natural river system can still be observed.