Iglesia de San Francisco, Cali, Colonial religious complex in central Cali, Colombia

The Iglesia de San Francisco is a religious center in downtown Cali comprising a neoclassical church, a Mudejar-style tower, a chapel, and a convent building. These structures together form a large compound that developed over time.

Franciscan missionaries started construction in 1757, completing the chapel and convent by 1764. The tower was added later and reflects how the site expanded gradually over the century.

The vault painted by Mauricio Ramelli depicts the life of Saint Francis of Assisi, from his youth to his death. The baroque main altar holds twelve small figures of the saint in different poses and seven life-size Franciscan saints, with the Risen Christ at the center. In the right side chapel, the Dead Christ on Calvary with Our Lady of Sorrows and John the Evangelist is among the most visited by locals.

The complex sits at the intersection of Carrera 6 and Calle 10 and is open for visits. Be aware that regular services take place, which may affect access at certain times.

The 23-metre Mudéjar tower is divided into four sections, with projecting cornices of trapezoidal and semicircular cut brick. Its bell openings have three-lobed arches with a ogee detail, and the walls carry diamond motifs. The historian Santiago Sebastián called it "the most beautiful Mudéjar tower in all of America".