Edificio Otero, National monument in central Cali, Colombia.

Edificio Otero is a three-story eclectic historicist building on the east side of Plaza de Cayzedo, next to the National Palace. Its walls follow the street lines, so its roughly rectangular plan has a cut corner holding the main entrance, above which rises a small dome with round windows. Vertical lines dominate the decoration, and the narrow windows are taller on the middle level than on the top floor.

Emiliano Otero bought the Ocampo house on Calle 12 facing Plaza de Cayzedo in 1916 and had it demolished for a new building designed by the Borrero y Ospina firm, erected between 1922 and 1926. It was Cali's first reinforced-concrete structure, an eclectic historicist design drawing on 19th-century French models with Renaissance and Baroque elements. The city's residents blocked its demolition and secured its declaration as a national monument on 25 July 1977.

The building once housed the Hotel Europa and Gambrinus restaurant, serving as a central gathering place where people conducted business and spent their social time. These establishments shaped how residents experienced downtown life in the city.

The building is easily accessible in central Cali and can be admired from the street to study its facade details and architectural style. Since it currently functions as office space, be aware that interior access may be limited.

In 1970 the building faced demolition but was saved through protests by architecture faculty from Universidad del Valle and local residents. This event turned it into a symbol of resistance against losing Cali's architectural heritage.