City National Bank, Neoclassical bank building in Galveston, Texas.

City National Bank is a 1920 Neoclassical building at 2219 Avenue D (Market Street) in downtown Galveston. Its exterior has a pedimented portico with Corinthian columns, and the interior features a barrel-vaulted ceiling. It was built for the bank founded by William Lewis Moody Jr. and later housed the Galveston County Historical Museum.

City National Bank was founded in December 1907 by William Lewis Moody Jr. and first operated in leased space in the Trust Building at 2228 Avenue E. Moody commissioned this $200,000 building at 2219 Avenue D, constructed in 1919–20. The bank took the name Moody National Bank in 1953; the building was listed on the National Register of Historic Places in 1984.

The building served as home to a museum that shared the region's history with visitors for decades. It was an important gathering place where people could learn about Galveston's past.

The building is visible from the street but is not currently open to the public as it has been closed since a major storm in 2008. You can still appreciate the exterior architecture and details from outside.

Mary Moody Northen, daughter of founder William Lewis Moody Jr., gave the bank building to Galveston County in 1972; it opened as the Galveston County Historical Museum in 1978. Hurricane Ike damaged its air and electrical systems in 2008, and the exhibits were moved to the Galveston County Courthouse.