López Serrano Building, Art Deco residential building in Vedado, Cuba

The López Serrano Building is an Art Deco residential structure in Vedado with fourteen floors and a central tower supported by ten steel columns above the main ten-story base. The apartments feature modern conveniences such as separate service entrances, hot and cold water systems, and geometric tile floor patterns.

Promoted by publisher José Antonio López Serrano, whose father José López Rodríguez ("Pote") had made a fortune from La Moderna Poesía and state printing contracts, the building was designed by architect Ricardo Mira in 1929. It was Cuba's tallest residential building until the FOCSA was built in 1956. Its steel frame was welded rather than riveted, since riveting technology was unavailable in Cuba.

The lobby walls are clad in book-matched Moroccan red marble panels, and on the elevator wall hangs El Tiempo, a nickel-silver relief by graphic designer Enrique García Cabrera. The elevator doors were originally nickel silver with Art Deco designs and pivot on hinges. The ground floor held shops, a barbershop, restaurants and coffee shops, as Havana zoning law required public commercial space facing Calle 13.

Visitors can best appreciate the building from the street, as the interior is typically not open to the public. The surrounding sidewalks in Vedado offer good vantage points to observe its architectural details and tower structure.

Eduardo Chibás, a congressman, senator and presidential candidate, lived in the fourteenth-floor penthouse and shot himself in August 1951 during a broadcast at the CMQ radio station; he died days later. The building's owner, publisher José Antonio López Serrano, was the son of banker José López Rodríguez, "Pote", who also took his own life, on 28 March 1921, leaving a fortune of 93 million dollars.