Colonial Life Arena, Multi-purpose arena in Columbia, United States

Colonial Life Arena is a multi-purpose arena in Columbia, South Carolina, with 18,000 seats for basketball and up to 19,000 for concerts, built for $64 million on 342,000 square feet. Its curved front carries a glass curtain wall, a band of cream-colored panels and a dark sign reading "Colonial Life Arena" with "HOME OF SOUTH CAROLINA BASKETBALL" and two gamecock logos. The building used 205,384 bricks, 3,848 tons of steel and 125 miles of cable.

Construction on the arena began in April 2001 to replace the Carolina Coliseum. It opened on November 22, 2002 as the Carolina Center, when 17,712 fans watched the South Carolina women beat Clemson 72–58; the official opening followed on December 2 with a 66–47 men's win over Temple. Unum acquired the naming rights in 2003, and on July 22, 2008 the USC board approved the name Colonial Life Arena.

The venue plays a central role in South Carolina's sports culture, hosting University of South Carolina Gamecocks basketball games and state competitions that draw passionate crowds. Fans fill the stands to support their teams throughout the season.

The arena stands at 33.99500, -81.03722, and its main entrance faces the A'ja Wilson statue, dedicated January 18, 2021. The building covers 342,000 square feet (about 31,773 m²) on a site that required 16,880 cubic yards of earth to be moved. Events are ticketed through Ticketmaster, and OVG360, formerly Spectra, manages the venue.

The facility was originally planned to host ice hockey, but the intended professional team never took up residence there. Instead, it became solely a venue for basketball and other entertainment events.