James B. Edwards Bridge, Box girder road bridge between Charleston and Mount Pleasant, United States

The James B. Edwards Bridge is a pair of pre-cast post-tensioned concrete box girder spans carrying Interstate 526 over the Wando River between Mount Pleasant and Daniel Island. Designed by Figg Bridge Engineers, it was built for six lanes with narrow shoulders but has been used for four since opening. The contractor was T.L. James Associates of Louisiana.

The bridge was built in the late 1980s to address growing transportation demands between Charleston and Mount Pleasant. This project represented a major infrastructure investment for the Charleston area.

The bridge honours James B. Edwards, who was governor of South Carolina, served as U.S. Secretary of Energy, and was long-time president of the Medical University of South Carolina. The span carries his name on I-526 between Mount Pleasant and Daniel Island.

The bridge carries four lanes of traffic, though it was built for six with narrow shoulders. Weekly inspections of its 92 post-tensioning cables have been carried out since a 2016 repair project. After a cable failure closed the westbound span on May 14, 2018, it reopened on June 2, 2018.

The bridge was built using a special construction method where precast concrete pieces were assembled from top to bottom. This approach helped protect the sensitive marsh areas surrounding the river during construction.