Mission San Carlos Borromeo de Carmelo, Spanish Catholic mission station in Carmel-by-the-Sea, United States.

Mission San Carlos Borromeo de Carmelo is a stone church with a tan facade, a central arched doorway, and a quatrefoil window above the door. A domed bell tower stands to the left and a square bell tower to the right, both topped with crosses. The church, begun in 1793 and finished in 1797, has a curved gable and two small stone figures flanking the entrance.

Founded in Monterey on 3 June 1770 by Junípero Serra, the mission moved to the Carmel River mouth in 1771, where Serra made it his headquarters until his death in 1784. Fermín Francisco de Lasuén then led it and began a stone church in 1793, completed in 1797. It headed all Alta California missions until secularization in 1833.

The name honors Charles Borromeo, a cardinal from Milan known for his reform work across Europe in the 16th century. Visitors today see furniture and everyday objects from the colonial period that show daily life of the missionaries and coastal peoples.

The mission is an active parish of the Diocese of Monterey, with a private school and two museums on its grounds. Visitors enter through the courtyard beside the church; the stone church, with its star window and flanking bell towers, is the focal point of the site. The grounds lie near the Carmel River mouth in Carmel-by-the-Sea.

Inside the chapel lies the tomb of Junípero Serra, who died here in 1784 and whose remains were later buried at this spot. Above his tomb hangs a small metal plaque that visitors often overlook, even though it marks the founder of California settlements.