Saint Nicholas Serbian Orthodox Cathedral, Serbian Orthodox cathedral in Hamilton, Canada.

Saint Nicholas Serbian Orthodox Cathedral stands at 149 Nash Road South in Hamilton, Ontario, and serves as the cathedral church of the Serbian Orthodox Eparchy of Canada. The church was consecrated on 20 June 1965, and its interior frescoes were painted by iconographer Dragomir Dragan Marunić between 1988 and 1990. The parish house stands south of the church.

The first church-school municipality dedicated to Saint Nicholas was founded in 1913 on land at Beach Road and Northcote Avenue, and its small church was consecrated on 15 December 1917 before being demolished when the steelworks expanded. In December 1963 the community resolved to build a new church; the land was consecrated in June 1964, foundations were dug from 5 October 1964, and the church was consecrated on 20 June 1965. It was proclaimed a cathedral on 18 December 1988.

The cathedral serves as a spiritual center for the local Serbian community, where traditional celebrations and religious ceremonies take place throughout the year. People gather here to maintain their connection to Orthodox faith and participate in important community occasions.

The cathedral is located at the intersection of Barton Street East and Division Street with street parking available nearby. The main entrance features a mosaic portal, and visitors can attend services or explore the interior when the building is open.

The frescoes were painted by iconographer Dragomir Dragan Marunić, who began with the altar and the left and right apses in February 1988, paused two years for lack of funds, then finished in 1990 with parishioners' donations. Bishop Georgije of Canada, Bishop Mitrofan of Toplica and Bishop Dositej of Marča served the liturgy at their consecration on 7 October 1990.