San Rocco Church, Catholic church in central Lugano, Switzerland.

San Rocco is a baroque church in central Lugano with a single nave covered by a barrel vault. An octagonal dome rises above the altar area, while the facade received its neo-baroque design during a 1910 renovation.

A church dedicated to Saint Blaise stood here from 1349 until its destruction in the 15th century. Construction of the present building began in 1528, stalled for lack of funds, and resumed in 1580 under the Confraternita di San Rocco, founded to invoke the saint against plague. Work ended in 1597 and the Bishop of Como, Feliciano Ninguarda, consecrated the church in 1602. The presbytery and side chapels were added in the 17th century, and Paolo Zanini rebuilt the facade in neo-baroque style in 1909–1910.

The church is named after Saint Roch, whose confraternity took over the building site in 1580 to invoke protection during plague epidemics. The dome and presbytery frescoes are by Carlo Innocenzo Carloni (1760), while the nave vault scenes of Saint Roch's life are attributed to Marco Antonio Pozzi's workshop. A modern Via Crucis by Nag Arnoldi runs along the side walls.

The church sits on Via Canova near Piazza San Rocco in the city center, making it easy to reach on foot from nearby areas. Visitors should know that access follows the church's religious schedule, so checking opening hours before your visit helps ensure you can enter.

The 1905 organ by Giuseppe Vedani sits on a wooden choir gallery and represents fine craftsmanship of its era. This instrument was built with two keyboards and a pedalboard that allowed musicians to create layered sounds during worship services.