Church of St. Jerome in Split, Gothic and Renaissance church in Varoš district, Split, Croatia.

The Church of St. Jerome is a house of worship combining Gothic and Renaissance styles, with detailed stone carvings visible both inside and outside. The building merges two different architectural periods in its structure and ornamental details.

The church was built in the 15th century on the site of an earlier church of St. Cyriacus. In 1480 Andrija Aleši carved the altar with reliefs of St. John the Baptist, St. Jerome and St. Anthony the Hermit, with a Pietà in the lunette. The hermitage cave beside it, the oratory of St. Cyriacus, was renewed in the second half of the 15th century. The Split canon Jeronim Natalis is buried in the church.

The church is also called sv. Jere, and the cave carved into the cliff beside it is the oratory of St. Cyriacus, restored in the second half of the 15th century. Local legend holds that St. Jerome and St. Cyriacus stayed in that hermitage. Canon Jeronim Natalis is buried inside the church.

The church stands on the southern slopes of Marjan, above the Varoš district, reached on foot by climbing the stepped lanes from the neighbourhood below. The hermitage cave known as the oratory of St. Cyriacus is cut into the rock face right beside the building, so both are seen on the same stop.

Beside the church, cut into the cliff itself, is a medieval hermitage cave rebuilt in the second half of the 15th century and known as the oratory of St. Cyriacus. Local legend holds that St. Jerome and St. Cyriacus stayed there, and the Split canon Jeronim Natalis was buried in the church.