Palazzo Colocci, Baroque house museum in Iesi, Italy.

Palazzo Colocci is a Baroque house museum in Iesi with a collection of artworks and historical objects spanning multiple periods. The building features a grand interior staircase within its courtyard, supported by columns and covered by a domed vault.

The Colocci family acquired the property in the 15th century and made it their residence. Over the following generations, the building underwent multiple transformations, with a major Renaissance redesign completed in the late 16th century.

The Colocci name comes from the family that owned the palace by 1435; Marquis Angelo Colocci, a humanist and philologist, obtained permission in 1475 to add a portico to the facade. The last descendant, Marchesa Cristina Colocci Vespucci, left a large part of the building and its paintings, sculptures, arms and family papers to Jesi for a museum of the lineage. The Casa Museo Marchese Adriano Colocci Vespucci reopened in 2013.

The museum is centrally located in the city at Piazza Angelo Colocci and is easily accessible on foot. The interior spans multiple levels, so plan to spend time exploring the different rooms and spaces throughout the building.

The Colocci family's last descendant, Marchesa Cristina Colocci Vespucci, left a large portion of the palace and its contents to the Comune of Jesi, including paintings, sculptures, arms, armour and family documents, on condition that a museum be created. The Casa Museo Marchese Adriano Colocci Vespucci reopened to the public in 2013 after years of closure.