Shinjuku Center Building, 54-floor skyscraper in Nishi-Shinjuku, Japan

Shinjuku Center Building is a 223-metre, 54-storey tower in Nishi-Shinjuku, Tokyo, with a pale grey facade of small rectangular windows set in vertical columns. Its flat roof carries a white box-like structure with a central antenna and a wider mechanical block at the right edge. The exterior walls have a brick-like brown finish.

Built on the site of the former Yodobashi water purification plant, the Shinjuku Center Building was completed on October 31, 1979 as the seventh tower of the Nishi-Shinjuku redevelopment and the centennial project of the Taisei Corporation, which still has its headquarters there. Ownership was split between Taisei, Tokyo Tatemono and Asahi Mutual Life Insurance; in 2008 Japan Prime Realty Investment Corporation bought Asahi's share for 21 billion yen.

Locals call it simply "Center Building". Its exterior walls are finished in brick-toned brown, and the basement and middle-basement levels hold more than 30 restaurants, shops and banks, including a post office branch. A passage links it to the Shinjuku Nomura Building, and the underground north passage from the West Exit Central Street gives direct access.

The building stands at Nishi-Shinjuku 1-25-1, a 7-minute walk from Shinjuku Station, 3 minutes from Tochomae Station on the Toei Oedo Line and 5 minutes from Nishi-Shinjuku Station on the Marunouchi Line. The underground north passage of the West Exit Central Street gives direct access, and a connecting passage links it to the Shinjuku Nomura Building. A paid car park holds 540 vehicles.

In 2009 the building became the first in the world to be retrofitted with 288 oil dampers against long-period ground motion, fitted on floors 15 to 39 while it stayed in use. During the 2011 Tōhoku earthquake the dampers cut top-floor deformation in the short-side direction by 22%, and by 51% in aftershocks.