Estes Kefauver Federal Building and United States Courthouse, Federal courthouse in downtown Nashville, United States.

The Estes Kefauver Federal Building & Courthouse Annex is a nine-story federal office building and courthouse in Nashville, built in 1952 with a nine-story annex completed in 1974. Designed by the Nashville firm Marr & Holman in the Modern Style, it stands at 801 Broadway and formerly housed the U.S. District Court for the Middle District of Tennessee.

Construction of the Estes Kefauver Federal Building began in 1948 to designs by the Nashville firm Marr & Holman, and the building opened in 1952 as a federal office building and courthouse. A nine-story annex was completed in 1974. After the Fred D. Thompson U.S. Courthouse opened nearby in 2022, the courts and other federal offices moved out, and the General Services Administration plans to keep the building for other federal agencies.

The building is named for Estes Kefauver, a U.S. Senator from Tennessee, as a tribute to his public service. The name was given to the federal building and courthouse in Nashville, where he was a well-known political figure. Visitors can see the name on the building's exterior signage.

The building stands at 801 Broadway in downtown Nashville. Courts and federal offices moved to the Fred D. Thompson U.S. Courthouse in 2022, so interior courtrooms are not open to visitors; the exterior can be seen from the street. The General Services Administration plans to keep the building for other federal agencies.

The General Services Administration plans to maintain the building and house other federal agencies currently scattered across Nashville, rather than sell it. Its courtrooms emptied after the Fred D. Thompson U.S. Courthouse opened nearby in 2022.