Catedral de São Luís, Portuguese colonial cathedral in São Luís, Brazil.

Catedral de São Luís is a Catholic cathedral in the heart of São Luís, recognizable by its white walls, twin bell towers, and large wooden doors. Inside, marble columns line a central nave that structures the space and draws the eye toward the altar.

The Jesuits Luís Figueira and Benedito Amodei began a college and church here in 1622, on the site of a hermitage left by French Capuchins. A new building designed by João Felipe Bettendorff rose from 1690, built with indigenous labour and inaugurated in 1699. After the Jesuits were expelled in 1759, the church became the city's cathedral in 1761, and its façade gained two towers in the early 20th century.

The cathedral remains an active place for the local Catholic community, where regular services and annual religious celebrations like the Feast of Our Lady of Victory bring people together. It reflects the spiritual importance this building holds for the city's identity.

The building is open to visitors daily, though it is considerate to be mindful during worship services since it remains an active place of worship. Contacting the parish office can provide more detailed information about the building and scheduled activities.

The gilded retable of the main altar was designed by the Jesuit João Felipe Bettendorff and carved by the Portuguese Manuel Manços with Maranhão craftsmen; it was listed by IPHAN in 1954. The Jesuit college beside the church held 5,000 volumes by 1760.