Our Lady of Guadalupe Cathedral, Ciudad Juárez, Catholic cathedral in Ciudad Juárez, Mexico

Our Lady of Guadalupe Cathedral in Ciudad Juárez is a religious building with neoclassical features including two three-tiered towers and Corinthian columns supporting a triangular pediment. The interior underwent major renovation after a fire and now blends modern stained glass windows with the original structure.

Fray García de San Francisco founded the Guadalupe de los Mansos Mission on 8 December 1659, and the Franciscan church was finished on 15 January 1668. Paso del Norte served as capital of New Mexico from 1681 to 1693. In the 20th century Father Baudelio Pelayo promoted a new cathedral attached to the old mission; it was consecrated in 1941 and completed in 1957, when it became the seat of the Diocese of Ciudad Juárez.

The cathedral is dedicated to Our Lady of Guadalupe, and the old Franciscan mission next door, founded on 8 December 1659 by Fray García de San Francisco, was called "La Reina de las Misiones" by historian Cleofas Calleros as the first mission in the region. Banners on the facade read "Solamente aceptando el amor hallarás la felicidad" and "50 años de Fe."

The cathedral stands in the Centro Histórico, attached to the preserved 17th-century Franciscan Mission of Guadalupe, so both buildings can be seen in one stop. The main entrance faces the plaza through the neoclassical portal with its two pairs of Corinthian columns and the clock in the pediment. The two towers were only finished in 1957, so the upper tiers and their small domes are the newest part of the exterior.

The cathedral stands attached to the preserved 17th-century Franciscan Mission of Guadalupe, founded on 8 December 1659 by Fray García de San Francisco. Historian Cleofas Calleros called that mission "La Reina de las Misiones" because it was the first in the region, and from it the local indigenous peoples were evangelized.