Nix Professional Building, Art Deco skyscraper in downtown San Antonio, United States.

The Nix Professional Building is a 23-story hospital in downtown San Antonio, Texas. When completed it was the largest and tallest hospital in the United States, and the only one housing doctors' offices, hospital beds and a parking garage in a single building. It ranks as the city's 10th tallest building.

Completed in 1930, the Nix Professional Building was the largest and tallest hospital in the United States at the time. It was also the only hospital combining doctors' offices, hospital beds and a parking garage in a single building. It now ranks as the 10th tallest building in San Antonio.

The building's name honours Dr. Aureliano Urrutia, the Mexican physician and surgeon who commissioned it and had it built as a combined hospital and office block. Its 23 floors held doctors' offices, hospital beds and a parking garage under one roof, a combination no other US hospital offered at the time.

The building is located downtown and is easily accessible on foot, with good views from street level. The entrance area with its large lanterns and canopy is the best spot for photography and viewing the architectural details.

At its 1930 opening the Nix Professional Building was the only hospital in the United States combining doctors' offices, hospital beds and a parking garage under one roof, and it was then the country's largest and tallest hospital. It remains the 10th tallest building in San Antonio.