Issaquena County, Administrative county in Mississippi Delta, United States.
The county spans 413 square miles of land and 28 square miles of water, featuring fertile bottomlands and hardwood forests along the Mississippi River.
Established in 1844 from Washington County's southern portion, the county seat moved from Skipwith to Duncansby before settling in Mayersville in 1871.
The name originates from Choctaw language meaning Deer River, reflecting the Native American heritage of the Mississippi Delta region.
The county administration operates from 129 Court Street in Mayersville, offering residents essential services through a five-member Board of Supervisors.
With 1,338 residents recorded in 2020, Issaquena County holds the distinction of being the least populated county east of the Mississippi River.
Location: Mississippi
Inception: 1844
Capital city: Mayersville
Shares border with: Washington County, Warren County, Sharkey County, Yazoo County, Chicot County, East Carroll Parish
GPS coordinates: 32.74000,-90.99000
Latest update: May 27, 2025 07:12
Poverty Point
41.1 km
USS Cairo
42.1 km
McRaven House
45.2 km
Holly Bluff Site
29.9 km
Mount Holly
39.8 km
Delta National Forest
19.5 km
Anchuca
44.2 km
Panther Swamp National Wildlife Refuge
40.8 km
5th United States Colored Heavy Artillery Regiment
35 km
Balfour House
44.9 km
Pemberton's Headquarters
44.9 km
Old Warren County Courthouse
44.4 km
Crescent Plantation
44.5 km
Uptown Vicksburg Historic District
44.8 km
Lower Mississippi River Museum
44.2 km
Hermione
41.1 km
Michigan Memorial
45.2 km
Scottland Plantation House
42.3 km
Fiske Theatre
39.6 km
Louisiana State Cotton Museum
22.3 km
Madison Parish Courthouse
41.4 km
Planters Hall
44.2 km
Lake Providence Commercial Historic District
18.3 km
Kings Crossing Site
40.9 km
Main Street Historic District
44.4 km
Grove Street-Jackson Historic District
44.5 km
Confederate Avenue Brick Arch Bridge
47 km
Biedenharn Coca-Cola Museum
44.4 kmReviews
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