Marie Selby Botanical Gardens, Botanical garden and historic site in Sarasota, Florida.

Marie Selby Botanical Gardens is a botanical garden located along the coast of Sarasota featuring large collections of tropical plants, orchids, and related species. The grounds span multiple thematic areas including a tropical conservatory and a museum dedicated to botany.

The gardens originated in the 1970s when Marie Selby left her private estate to the public. This founding transformed a personal residence into a center for botanical research and education.

The Christy Payne House, listed on the National Register of Historic Places in 1998, holds the Museum of Botany and the Arts, showing changing exhibits of botanical art and photography. The garden's journal Selbyana has been published twice a year since 1975, and the Mulford B. Foster Bromeliad Identification Center, opened in 1979, keeps taxonomic files on over 2,800 bromeliad species.

The grounds are walkable and offer various paths through the garden areas. It helps to wear comfortable shoes and allow time to explore all the collections at a relaxed pace.

The Spirit Collection holds nearly 28,000 vials of flowers in preservative fluids, the second-largest of its kind in the world after the Royal Botanic Gardens, Kew. About 24,000 of the vials contain orchid flowers. The gardens' botanists have discovered or described more than 2,000 plant species previously unknown to science.