Downtown Sarasota Historic District, Historic district in Sarasota, Florida.

Downtown Sarasota Historic District is a 19-acre (7.7 ha) historic district in Sarasota, Florida, bounded by 1st Street, Orange Avenue, State Street, Gulf Stream Avenue and North Pineapple Avenue. It holds 51 buildings, six of them individually listed on the National Register: the American National Bank Building, DeMarcay Hotel, Kress Building, Roth Cigar Factory, Edwards Theatre and Worth's Block. The district was added to the National Register on April 9, 2009.

The district grew during Sarasota's early development between 1909 and 1959, as the city transformed from a trading post into a more prosperous place. Official recognition as a historic area came in 2009 to protect the building styles and structures accumulated over those decades.

Six of the district's 51 buildings are individually listed on the National Register: the American National Bank Building, DeMarcay Hotel, Kress Building, Roth Cigar Factory, Edwards Theatre and Worth's Block. The Edwards Theatre is a theatre, not an opera house. The district was added to the National Register on April 9, 2009.

The district lies east of Sarasota Bay, with Gulf Stream Avenue along its bayfront edge and North Pineapple Avenue at its eastern boundary. The 19-acre grid is flat and walkable, and the six individually listed buildings serve as orientation points among the 51 structures. Start at the bayfront and work inland to cover the blocks in sequence.

The Roth Cigar Factory shows Sarasota's past as a place where tobacco products were made and shipped. This building reminds visitors that the area once thrived on manufacturing before becoming known for culture and the arts.