Horn Creek Baptist Church, Protestant church in Edgefield County, South Carolina, United States.

Horn Creek Baptist Church is a white wooden building set on a gentle slope with symmetrical windows and a centered entrance door. The structure displays classic features typical of rural churches from the early period of American religious architecture.

The building was established around 1790 and received its National Register of Historic Places designation in 1971, confirming its long significance in South Carolina. This listing recognized its value as a testament to early American church architecture.

The church was one of the region's "mother" churches, and daughter congregations such as Big Stevens Creek Baptist Church and Kiokee Baptist Church trace their roots to Daniel Marshall's ministry. Its pastor for nearly forty years was Reverend John Landrum, an Edgefield pottery entrepreneur who owned the enslaved potter Dave, so Dave may have attended services here.

The church stands in a remote rural setting, so plan your own transport and allow time to walk the churchyard and cemetery. Services were discontinued in 1942; the property is held by the Edgefield County Historical Society, and a caretaker has lived on site since 2015, which ended the earlier vandalism.

The church is one of only two surviving structures tied to Edgefield's pottery heritage, because its pastor for nearly forty years was Reverend John Landrum, owner of the enslaved potter Dave. Dave likely attended services here. The building also served both white and African American worshippers in its early decades.