National Historic Trails Interpretive Center, Interpretation center in Casper, Wyoming, United States.

The National Historic Trails Interpretive Center is an 11,000-square-foot interpretive center northwest of Casper, Wyoming, on Interstate 25. Its permanent exhibits cover the four trails that ran together through Wyoming: the Oregon, Mormon Pioneer, California, and Pony Express trails. It also hosts temporary traveling exhibits and multimedia presentations, and is run by the Bureau of Land Management, the City of Casper, and the National Historic Trails Center Foundation.

The center documents the journeys of hundreds of thousands of people who traveled the Oregon, Mormon, California, and Pony Express routes between 1841 and 1868. These routes were central pathways of American westward expansion during that era.

The permanent exhibits are organized around the four trails that ran together through Wyoming: the Oregon, Mormon Pioneer, California and Pony Express trails. The center also hosts temporary traveling exhibits alongside these permanent displays, and admission is free.

The center offers orientation services, information about the historic trails, and a gift shop for visitors. The facility includes restrooms and accessible options for people with mobility needs.

The center was renamed the Barbara L. Cubin National Historic Trails Interpretive Center by Public Law 119-117, enacted on September 25, 2026. The building covers 11,000 square feet and sits on 10 acres donated by the City of Casper. It is run by a partnership of the Bureau of Land Management, the City of Casper and the National Historic Trails Center Foundation.