Palazzo Grande, Multi-purpose palace in Piazza Grande, Livorno, Italy

Palazzo Grande is a multi-purpose palace in Piazza Grande, Livorno, featuring stone-clad walls with arched openings on the ground floor and rectangular windows arranged in modular patterns on upper levels. The building contains separate sections for residential units, office spaces, and a cinema complex with multiple function rooms.

After World War II bombing destroyed Livorno's centre, a 1947 ideas competition for Piazza Grande produced no winner; the scheme by Luigi Vagnetti, presented by the Società Immobiliare in early 1948, was approved despite opposition. Work began in 1950 and the building was finished in 1952, closing the square opposite the Palazzo Comunale.

Locals nicknamed the building the "Nobile interrompimento" (noble interruption) for the way it cuts the old Piazza Grande in two, and many never fully accepted it, still regretting the wide square that once inspired the English architect Inigo Jones. The cinema-theatre on its rear side opened on 25 March 1952 with the revue "Gran baldoria" by Garinei and Giovannini, and after a long closure was converted into a three-screen multiplex before shutting down in summer 2013.

The palace stands between Piazza Grande and the Municipio square, closing the space in front of the Duomo. A cross-shaped gallery runs through both blocks, with vertical circulation at its intersection. The cinema on the Municipio side closed in summer 2013, so it is not open for screenings.

The ceramic chimera on the Piazza del Municipio front is among the last works of Duilio Cambellotti, made in 1952, the year the building was finished. The cinema block behind it ends in a roof of triangular modules, and the three-screen layout came from walling up the upper gallery.