Riserva Naturale Regionale Sentina, Regional nature reserve in San Benedetto del Tronto, Italy.

Riserva Naturale Regionale Sentina is a protected area along the Adriatic coast north of the Tronto River mouth. The terrain features sandy ridges, wetlands, and salt meadows that together create different environments for wildlife in a small area.

The wetland, known as Sentina, was long subject to attempts at full reclamation for agriculture, yet a salt marsh survived. It was established as a regional nature reserve by regional council resolution no. 156 of 14 December 2004. The Torre sul Porto, a watchtower built between 1543 and 1547 against Saracen raids, stands within the reserve.

Several trails carry local names: Sentiero di Strëchì recalls the Cipolloni family, called Trëchì, who lived at the Torre sul Porto, and marks the old boundary between the Laureati estates to the north and the Sgariglia estates to the south. The Strada per Olivo e Sina is named after the tower's last residents, while the Sentiero del Palazzo takes its name from an early-20th-century Sgariglia building known as the Palazzo.

Visitors can explore marked walking and cycling paths throughout the area, which link to larger regional routes. The trails are well maintained and easy to follow.

The Torre sul Porto, built between 1543 and 1547 as a watchtower against Saracen raids, still stands inside the reserve; the paths Strada per Olivo e Sina and Sentiero di Strëchì are named after the families who lived there. The reserve is also an Important Bird Area, code 087.