Martyn Brothers House, Federal heritage building on Bolshaya Sadovaya Street, Rostov-on-Don, Russia.

The Martyn Brothers House is a two-story red brick building that merges Russian and German architectural styles with Gothic Revival features on its facade. It stands at the intersection of Bolshaya Sadovaya Street and serves as a cultural venue within the grounds of the former fortress.

Built in 1893 by architect Nikolai Sokolov, the house originally belonged to Ivan Romanovich Martyn, a merchant with British citizenship. During the 1910s, his relative George Martyn hosted official receptions there while serving as United States Consul.

The name comes from the Martyn family, British subjects who owned the house and the nearby John Martyn and Co. ironworks. In the 1910s George Martyn served as US Consul and received visitors in the building. Since 22 May 2015 it has been the Sholokhov Centre, opened for the writer's 110th birthday; its first exhibition, "Traces of Cossack Antiquity", showed artefacts from the Hermitage collections.

The house stands at the corner of Bolshaya Sadovaya Street and Fortress Lane, in the centre of the former Fortress of Saint Dimitry of Rostov. It reopened as the Sholokhov Centre on 22 May 2015 after repairs from 2008 to 2014. The centre serves as an exhibition space and hosts lectures, museum classes and theme nights.

The building now hosts the Sholokhov Centre, which displays works from the State Hermitage Museum, creating an unexpected link between this private house and one of the world's largest art collections. This partnership transformed a 19th-century merchant residence into a venue for major museum exhibitions.