St. Nicholas in Butki, Eastern Orthodox temple in Serpukhov, Russia.

St. Nicholas in Butki is an Orthodox temple featuring Moscow Baroque architectural style located in Serpukhov. The building displays traditional elements of religious architecture from its era of construction.

A wooden church stood on this site by the first half of the 16th century. The brick church was built in 1711; a side chapel and refectory were added in 1780–1788, the altar was rebuilt in 1838, and the bell tower was rebuilt in the Empire style in 1850. Closed and partly destroyed in the 1930s, it was restored from the 2020s, and services resumed in 2025.

The church stands in Zanarye on Chernyshevskogo Street, formerly Butkinskaya Street, which gave the district its name. Its patronal feast honours St Nicholas the Wonderworker. The hieromonk Andrei, born Andrei Semyonovich Alekseyev in 1872, served here before his arrest on 2 October 1937 and execution on 21 October 1937 at the Butovo firing range.

The church stands in Zanaurye on Chernyshevskogo Street, formerly Butkinskaya Street, on the left bank of the Nara. Restoration began in the 2020s, and services resumed in summer 2025, so access may still be limited by ongoing works.

The church kept its original three-part layout — church with altar, vestibule and bell tower on one axis — until the 1930s, when the bell tower and the cupolas were destroyed. The refectory is small and matches the length of the church itself, and the building has no lower podklet floor.