St. George's Cathedral, Užice, Serbian Orthodox cathedral in Užice, Serbia

St. George's Cathedral is a single-nave church with a semicircular apse and rectangular choir spaces. Its west facade has two blind arched windows and one rectangular window below an icon of St. George; the south door is topped by a pointed Turkish arch. Inside, Doric pilasters divide the nave into four bays, and the narthex has a barrel vault.

Construction began in 1842 under architects Nastas Stefanović and Paun Antonijević from Kragujevac, after Užice's administration resolved on 6 February 1840 to build a new church and Prince Mihailo Obrenović approved a 20,000-groschen loan. The church was consecrated in 1844 by Bishop Nikifor Maksimović. A fire in November 1955 destroyed twelve icons on the right side of the iconostasis and damaged frescoes, prompting restoration led by the Belgrade Institute for Monument Protection.

The church is dedicated to St. George, whose icon stands above the west entrance. The choir walls show frescoes of Serbian saints including St. Sava, St. Uroš, St. Stefan Dečanski, St. Milutin, St. Simeon, St. Lazar, St. Jovan, St. Angelina and St. Stevan Štiljanović. The south wall inscription records that Milija Marković and Dimitrije Posniković from Karlovac completed the frescoes and iconostasis at Ascension 1851.

The church stands at Sveti Sava Square on Žička Street, near the Đetinja river, with the town hall, court, museum and market nearby. A separate chapel beside the church, built in 1998, is used for lighting candles. The churchyard was landscaped and the two church shops selling icons and candles were enlarged.

The oldest bell, donated in 1846 by Prince Aleksandar Karađorđević, was cast in Stefan Bota's workshop in Vršac. A second bell was removed by Austrian forces in 1916, likely melted into cannonballs. Two memorial plaques flanking the main entrance list 279 soldiers from Užice and nearby villages who died between 1912 and 1918.