Scott's Run Nature Preserve, Nature reserve in Fairfax County, United States.

Scott's Run Nature Preserve is a 336-acre woodland in McLean, Virginia, bordered by State Route 193, Interstate 495 and the Potomac River. Its namesake stream, Scott's Run, rises in Tysons Corner and enters the Potomac on the northwest side. The preserve is noted for eastern hemlocks, rare in this area, and is operated by the Fairfax County Park Authority.

The land was acquired in the 1920s by Edward B. Burling and nearly became a development site in the 1970s. Local residents organized a major fundraising effort to purchase and protect the property as a nature preserve.

The name comes from a nearby stream, and the preserve serves as a retreat for local residents seeking solitude in nature. People use the trails regularly to walk, observe wildlife, and escape the busy surroundings of the suburbs.

The preserve has strict rules against swimming, picnicking, and unleashed pets, with limited parking available. Wear sturdy shoes since the trails are steep and can be slippery after rain or during wet seasons.

Eastern hemlock, rare in this part of Virginia, grows in the preserve's cool, moist ravines. The species is named for the resemblance of its crushed foliage to the scent of the unrelated poison hemlock plant.