The Propylaeum, Cultural center and historic residence in Indianapolis, United States.

The Propylaeum, also known as the John W. Schmidt House, is a three-story Neo-Jacobean building at 1410 North Delaware Street in Indianapolis. Built of red brick with limestone trim, it has a full basement, a slate hipped roof with several gables, a wraparound verandah, a square tower, and a porte-cochère.

Built in 1890–91 as the home of John William Schmidt, president of the Indianapolis Brewing Company, it passed to brewer Joseph C. Schaf in 1905. The College of Music and Fine Arts bought it in 1921 but defaulted, selling it in 1923 to the Indianapolis Propylaeum association, which had lost its original North Street clubhouse to the Indiana World War Memorial Plaza.

The name comes from the Greek propýlaion, a monumental gateway to a city's sacred precincts, chosen in 1888 to signal a gateway to higher culture. The association's tea room opened in September 1924 and still operates. The house is rented for private events and hosts public cultural programming.

The house stands at 1410 North Delaware Street, north of downtown Indianapolis, near the intersection with Fourteenth Street. Its red brick and square tower make it easy to pick out from the sidewalk. The association rents the clubhouse for private events, and its tea room, opened in September 1924, still operates.

The name comes from the Greek word propýlaion, meaning a gateway or entrance, reflecting the house's role as a threshold to education and social advancement for women. This symbolic meaning of a passageway was a deliberate choice by those who established the institution.