National Blues Museum, Music museum in downtown St. Louis, US

The National Blues Museum is a music museum in downtown St. Louis with rooms containing artifacts, recordings, and displays that show how this musical form developed over time. The spaces are organized so visitors can follow the different phases of this music's history.

The National Blues Museum opened on April 8, 2016, in a renovated historic building in downtown St. Louis, built at a cost of $14 million. Surly King, daughter of B.B. King, spoke at the opening. In the 2023–24 NHL season the St. Louis Blues partnered with the museum for pre-game performances and STEM outreach. It closed on March 27, 2026, citing economic challenges and falling visitor numbers.

The museum's name and subject refer to the blues, the African American music whose history and impact the institution explored. Its Lumiere Place Legends room hosted live performances, and in the 2023–24 NHL season the St. Louis Blues hockey team partnered with the museum for pre-game performances and STEM-focused community outreach.

The museum closed permanently on March 27, 2026, so there are no visiting hours to plan around. Its former home was a renovated historic building in downtown St. Louis, near the Gateway Arch grounds. Anyone researching a trip should confirm the closure before travelling, as the building no longer operates as a museum.

On certain evenings, the museum hosts live performances where local and visiting musicians play on stage and audiences experience the music in a small, intimate setting. These sessions connect the museum's historical focus with contemporary music from that tradition.