Post Office Palace, Eclectic government building in República district, São Paulo, Brazil.

The Post Office Palace is an eclectic building in the Anhangabaú Valley, in São Paulo's Historic Center. Its 15,000 m² complex has a four-storey main block with a basement and a three-storey secondary block. The facade is divided into three parts: the central section facing Pedro Lessa Square has columns framing second- and third-floor windows, the side facing Avenida São João has narrow windows with treated lintels, and the third-floor windows are full-arched. A clock crowned by two ornamental human figures tops the main facade.

The building was completed in 1922 during Brazil's centenary celebration of independence and replaced an inadequate postal facility following a presidential visit in 1918. This new construction marked a turning point in the country's postal infrastructure development.

The Post Office Cultural Center opened here in 2013 with two exhibition halls and closed in October 2023; the Central Post Agency still operates in the building. Its free program mixed humanities, music and visual arts, showing renowned and emerging artists together. Exhibitions included O Rio de Debret, 120 watercolors by Jean-Baptiste Debret, Elifas Andreato's works in 2016, and Marcos Amaro's Sobrevoo in 2017.

The site is centrally located in the República district and easily accessible by public transportation. Visitors should check hours in advance as the place functions both as a working postal facility and a cultural venue.

The main facade is crowned by a clock flanked by two purely ornamental human figures. Three plaques in the public lobby record the 1922 inauguration and the two later renovations of the building.