Manuripi-Heath Amazonian Wildlife National Reserve, Nature reserve in Pando Department, Bolivia.

Manuripi-Heath is a nature reserve covering vast Amazon rainforest in northern Bolivia, shaped by rolling hills, elevated plateaus, and wide river plains. Three major river systems flow through the landscape, creating diverse habitats that support complex ecosystems throughout the region.

The reserve was created on 20 December 1973 by Supreme Decree 11252 as the Reserva Nacional Amazónica del Manuripi-Heath, covering about 1,892,000 hectares. A 1998 recategorisation study proposed new limits between the Manuripi-Orthon and Madre de Dios rivers, and Supreme Decree 25906 of 22 September 2000 renamed it and cut it to roughly 747,000 hectares. SERNAP took over its administration in July 1999, and the first management committee formed in 2008.

Local communities within the reserve maintain traditional practices of rubber extraction and Brazil nut collection, contributing to sustainable resource management.

Visitors need to arrange permits and proper supplies well in advance, as access is limited and facilities are sparse. The tropical climate brings high temperatures and substantial rainfall year-round, making weather-appropriate gear essential for any trip.

The reserve shelters around 1,000 bird species, alongside jaguars, pumas, capybaras, monkeys, caimans and a wide range of fish. Its forests hold Brazil nut, cedar, rubber trees and many palms. It is also home to the Tacana, Pacahuara, Iñapari and Araona indigenous peoples.