Red Cross House, Commercial heritage building in Sydney, Australia

Red Cross House stands at 153-159 Clarence Street and is a steel-frame building with mushroom-head column construction and Art Deco elements from the late 1930s. Windows with curved terminations and steel frames define the appearance of the facades facing Clarence and Kent Streets.

The building was constructed from 1937 to 1938 based on designs by Samuel Lipson working with Robertson, Marks and McCredie. Architects developed it as a commercial building for S. Hoffnung & Co., later converted to serve blood transfusion operations.

The building carries the name of its longest public use: the Australian Red Cross bought it in July 1970 and ran offices and a blood donor centre here until 2010. It was sold in 2011 and is now known simply as 155 Clarence Street, so the old name survives mainly in heritage listings.

The building is a working office address at 153–159 Clarence Street, between Kent and Clarence Streets in Sydney's western CBD, a short walk from Wynyard station. There is no public entry or visitor access; the 2013–2015 redevelopment added three office levels behind the conserved facades. Look up from the pavement on both street frontages to see the curved window terminations.

The building's architect, Samuel Lipson, was born in Leeds in 1896 to a family of Lithuanian descent and trained at the Glasgow School of Art before migrating to Australia in 1925. He alone prepared the development drawings, though Robertson, Marks and McCredie share the credit.