Casa Grande, Mount Isa, Heritage-listed residence in Mount Isa, Australia.

Casa Grande is a two-storeyed, U-shaped Spanish Mission style house on Nettle Street in Mount Isa, built in 1949 of 6-inch Denaro bricks with stuccoed white walls, dark timber-framed sash windows, terracotta roof tiles and balconies. Its verandahs, supported by roughly hewn timber posts, overlook a central courtyard, and the house stands on a rise above the mine.

The residence was built in 1949 for Julius Kruttschnitt II, General Manager of Mount Isa Mines, during the post-World War II mining expansion. Its construction reflects the economic prosperity that the growing mining industry brought to the region.

The name Casa Grande, Spanish for "big house", is a term used in Arizona and New Mexico for the boss's house, echoing Kruttschnitt's American background. The Kruttschnitts held a housewarming under a marquee on the lawns on 22 July 1950, and an annual New Year's Eve punchbowl party was among their functions. In 1951 Mrs Kruttschnitt arranged a dinner for 80 long-serving employees and their wives.

The building is situated in a residential area of Mount Isa and can be viewed from the street. It is easy to include in a walking tour of the town to observe the architectural style of the period.

A suite at Casa Grande was redecorated and refurnished for Queen Elizabeth's 1970 visit to Mount Isa, and the company bought a dining table with a top cut from a single piece of cedar for the occasion. The house had become a guest house for visiting directors and VIPs in 1966.