San Bernardino de Sena Estancia, Mission outpost museum in Redlands, California, United States.

The San Bernardino de Sena Estancia is a six-room building with a chapel and a freestanding bell wall, built in 1926–1937 on the site of the original asistencia. It replaced the ruined chapel using salvaged historic materials, and its design took artistic license since funds did not allow restoring the rancho itself. It stands at 26930 Barton Road in Redlands.

The estancia was established in 1819 as a ranch outpost of Mission San Gabriel Arcángel, used for grazing cattle and for the reduction of Serrano and Cahuilla people into Mission Indians. A second estancia was built around 1830 at the Politana rancheria, about 1 mile from the 1819 site. After secularization in 1833–34, the 1842 Rancho San Bernardino land grant to the Lugo family and Jose Diego Sepulveda included the chapel, tile kiln, lime kiln and grist mill. The property passed to Mormon leaders Charles C. Rich and Amasa Lyman in 1851, then to Dr. Ben Barton in 1859.

The site's name comes from Bernardino of Siena, the 15th-century Franciscan preacher, and the chapel and courtyard are rented for weddings and other events. The Redlands Conservancy has run the property since November 2018, after it was transferred from the San Bernardino County Museum.

The grounds are accessible on select days, with guided tours available by advance reservation. Visitors should check current hours and access requirements in advance, as these can vary.

The chapel and courtyard now serve as spaces for weddings and community events. This conversion shows how historical sites continue to be living gathering places for local communities.