Redlands Santa Fe Depot District, Railway complex in downtown Redlands, United States.

The Redlands Santa Fe Depot District is a historic commercial district in downtown Redlands centered on its Atchison, Topeka and Santa Fe Railway depot. The current station building, a Classical Revival structure, was built in 1909–10 to replace the 1888 depot. Around it stand former orange packing houses and three buildings from the city's historic Chinatown; the depot was restored and integrated with the adjacent Redlands–Downtown station in 2022.

Rail service arrived in Redlands in 1888 and made the town a key transportation hub for the region's orange industry. The station became the center of local trading networks.

The district preserves buildings from the 1880s Chinatown area, showing how Chinese workers shaped local development. These structures tell the story of people who helped build the community.

The district centres on the depot at Orange Street in downtown Redlands, and the surrounding packing houses and Chinatown buildings can be seen on foot from the street. The depot was restored and linked to the Redlands–Downtown station on the Arrow commuter rail line in 2022, so arriving by train is an option. Shops and restaurants occupy the redeveloped Packing House District, completed in 2024.

The Pacific Electric Red Car trolley, running the Redlands Line along Orange Street, passed the mainline depot between 1903 and 1936. The depot itself lost passenger service in 1938. Three buildings from the city's Chinatown, active from the 1880s to the 1920s, stand in the district.