Café de Tacuba, Historic restaurant in Centro Histórico, Mexico City, Mexico.

Café de Tacuba is a restaurant in Mexico City's historic center with multiple dining rooms that receive natural light from large windows. The interior combines handpainted Talavera tiles with Mexican artwork and traditional wooden furniture throughout.

Dionisio Mollinedo arrived from Villahermosa, Tabasco, and opened the Café de Tacuba on 12 October 1912 in a 17th-century mansion on Calle de Tacuba that had housed a dairy. In 1922 Diego Rivera and Guadalupe Marín held their wedding banquet here. On 25 June 1936 the governor-elect of Veracruz, Manlio Fabio Altamirano Flores, was shot dead at one of its tables; no one was convicted. A fire damaged the main room's furniture in 1999, and the restaurant reopened that July.

The restaurant's name comes from Calle de Tacuba, where it opened in 1912; the band Café Tacvba later took its name from the café, changing the u to a v. From Wednesday to Sunday the group Tuna Bohemia del Estado de México moves between the tables playing Spanish, Mexican and instrumental music. The walls hold colonial-era paintings, Puebla mosaics and stained glass.

The restaurant sits at Calle de Tacuba 28, between Allende and República de Chile, a few blocks from the Zócalo and roughly halfway to the Alameda Central; the Allende metro station on Line 2 is nearby. It serves breakfast, lunch and dinner daily, from 8 am to 11 pm. Tuna music is played Wednesday to Sunday.

The band Café Tacvba took its name from the restaurant after moving to Mexico City from Ciudad Satélite, changing the u to a v to avoid legal problems; the success of the band made the café's name known beyond Mexico.