San Francisco Plantation House, Historic plantation house in Reserve, Louisiana

San Francisco Plantation House is a 1+1⁄2-story house on a full-height basement, set on about 8 acres in Reserve, Louisiana, on the north bank of the Mississippi River behind Highway 44 and a levee. Side-facing divided staircases lead to the main floor, sheltered on three sides by an ornate porch on fluted columns with iron Corinthian capitals. A deeply overhanging decorative cornice gives it the profile called "Steamboat Gothic", topped by a dormered hip roof.

The house was built in 1853–1856 for Edmond Marmillion, possibly incorporating elements of an older building. Its name comes from his son Valsin's remark that he was sans fruscins, "without a penny in my pocket," which became St. Frusquin and then San Francisco in 1879 under the next owner, Achille D. Bougère. It was declared a National Historic Landmark in 1974.

The name "San Francisco" comes from Valsin Marmillion's remark that he was sans fruscins, "without a penny in my pocket," over the estate's debt; it became St. Frusquin and was changed to San Francisco in 1879 by Achille D. Bougère. Inside, ceiling and door panels carry paintings attributed to New Orleans artist Dominique Canova.

The house stands on the north bank of the Mississippi, separated from the river by Louisiana Highway 44 and a levee, on about 8 acres now surrounded by the refinery's oil tanks. It was open as a museum and event facility until 2022, so check current access before planning a visit. The site is in Reserve, St. John the Baptist Parish.

The name comes from Valsin Marmillion's remark that he was "sans fruscins", without a penny, when he took over the heavily indebted estate. The phrase became St. Frusquin and was changed to San Francisco in 1879 by the next owner, Achille D. Bougère.