Black Creek Wilderness, Nature reserve in Mississippi, United States

Black Creek Wilderness is a nature reserve within De Soto National Forest that encompasses thousands of acres shaped by its namesake river system. The waterway displays a distinctive brown color from natural tannins and creates extensive wetland zones along its banks.

Black Creek Wilderness was designated a federal wilderness area in 1984 under the Wilderness Act, within De Soto National Forest. In 1986, 21 miles of Black Creek, a Pascagoula River tributary, became Mississippi's only National Wild and Scenic River, classified as "scenic". The protection keeps a coastal plain landscape of longleaf pine uplands and hardwood floodplain that predates forest clearing and river damming.

Black Creek is Mississippi's only National Wild and Scenic River; 21 miles (34 km) of it were designated in 1986 and classified as "scenic". The creek's caramel color comes from tannic acid released by decaying vegetation. White sandbars serve as picnic spots and primitive campsites, and canoeing the corridor is a common way to see the floodplain.

The 41-mile Black Creek Trail follows the creek drainage, with about 10 miles crossing the wilderness. White sandbars serve as picnic and primitive camping spots, and several public landings give boat access for canoeing. Summer weekends are the busiest time for day trips and floating.

Black Creek is Mississippi's only National Wild and Scenic River: 21 miles (34 km) of it were designated in 1986 and classified as "scenic". The 41-mile (66 km) Black Creek Trail follows the creek drainage, and about 10 miles (16 km) of it pass through the wilderness.