Maj. James B. Bailey House, Antebellum plantation residence in Gainesville, United States.

The Maj. James B. Bailey House is a two-story wooden building in Gainesville featuring plantation-style architecture. It has broad verandas and symmetrical design elements set on land spanning nearly one acre.

Major James B. Bailey, an early settler who owned large tracts of land in Gainesville, began building the house perhaps around 1848. He is thought to have pushed for moving the Alachua County seat from Newnansville to Gainesville. The house was documented by the Historic American Buildings Survey and listed on the National Register of Historic Places in 1972.

The house shows how wealthy landowners in pre-Civil War Florida chose to live and build their homes. The broad verandas and symmetrical design reflect the tastes and status of the planter class.

The house stands at 1121 Northwest 6th Street in Gainesville, north of the city centre. It is a private residence, so visitors see it from the street; the Historic American Buildings Survey measured drawings and data pages document the structure for those who cannot enter.

The house was recorded by the Historic American Buildings Survey, which produced 12 measured drawings and 4 data pages. These records document its plantation architecture and are available for researchers and visitors interested in Gainesville's early settlement.