National Shrine of St. Francis of Assisi, Roman Catholic church in San Francisco, California, United States

The National Shrine of St. Francis of Assisi is a Norman Gothic Catholic church in North Beach, San Francisco. Its white facade has two tall square towers with gold crosses, a rose window and three pointed portals; a second view shows a left tower with one spire and a right tower with three. The 1860 exterior walls, including the twin campanile, survived the 1906 earthquake and fire, and the rebuilt interior was rededicated in 1919. Inside is a 1926 Schoenstein pipe organ, enlarged in 1993.

The original church was founded to serve the growing Catholic community during the gold rush starting in 1849, first in a simple wooden building. After the 1906 earthquake, the sturdy brick walls survived but the interior burned, and the church was rebuilt and reopened in 1919.

The church is also the National Shrine of St. Francis of Assisi, a title it received in September 1999. Its name honours the 12th-century founder of the Franciscan order, and the parish's early sermons were preached in Latin, Spanish, Italian, French, Chinese and German for gold-rush worshippers. Next door stands La Porziuncola Nuova, a 2008 replica of the small chapel Francis founded in Assisi, guarded by the Knights of St. Francis.

The shrine opens daily from 10 in the morning until 5 in the afternoon, with a member of the Capuchin Franciscan community present to welcome visitors and assist with prayer or quiet reflection. Mass is held on Sundays at 10 in the morning and on weekdays at noon, with confession available from 11:30 before weekday Mass.

The shrine houses a replica of the Porziuncola, a small chapel built by Saint Francis in Italy, offering visitors a space for quiet contemplation. This replica connects the site to Francis's origins and allows pilgrims to engage with the healing and spiritual practices associated with that holy location.