Dos Amigos Pumping Plant, Pumping station in Merced County, California.

Dos Amigos Pumping Plant is a water pumping station in the San Joaquin Valley, built between 1963 and 1966 as part of the California State Water Project. It is the second pumping plant on the California Aqueduct and the South Bay Aqueduct, with six units that lift water 118 feet (36 m) at a design flow of 15,450 cubic feet (437 m3) per second. It stands along Interstate 5, about 10 miles (16 km) south of Los Banos in Merced County.

This pumping station was constructed between 1963 and 1966 and served as the second major pumping facility for the California Aqueduct system. It was built as part of the state's water infrastructure development.

The plant lifts water from the O'Neill Forebay into the California Aqueduct, which runs about 444 miles from the Clifton Court Forebay in Sacramento to Southern California. Its name, Spanish for "two friends", is shared with the nearby Dos Amigos area along Interstate 5. The aqueduct it feeds splits into West, East and Coastal branches.

The plant sits along Interstate 5 in the San Joaquin Valley, about 10 miles (16 km) south of Los Banos in Merced County. It is an operating industrial facility, not open to the public; the pumps and pipelines are seen from the freeway or from outside the grounds. Coordinates are roughly 36.92° N, 120.83° W, at an elevation of 282 feet.

Dos Amigos is the second pumping plant on the California Aqueduct, lifting water 118 feet with six units that together move 15,450 cubic feet per second at design head. The plant sits at an elevation of 282 feet, about 10 miles south of Los Banos along Interstate 5.