Holy Rosary Cathedral, Roman Catholic cathedral in Regina, Canada.

Holy Rosary Cathedral at 13th Avenue and Garnet Street in Regina is the cathedral church of the Roman Catholic Archdiocese of Regina. Designed by Joseph Fortin's Montreal firm after churches in northern France, it is a Romanesque Revival building faced in yellow brick with limestone accents, built 1912–1917 by Smith Brothers & Wilson at a final cost of $135,000. Its light, airy interior is decorated sparingly, in keeping with Canadian taste.

Construction began in 1912 and was completed in 1917, reflecting growing Catholic communities in the region. This project represented a major investment in both architecture and religious life for Regina during the early 20th century.

The cathedral's gallery organ was built by Casavant Frères of Saint-Hyacinthe, Quebec, in 1930, replacing a large reed organ. Repaired after the 1976 fire and renovated in 1992–1993, it was named The McGuigan Organ after Sister Marion McGuigan, a local educator and humanitarian. The Institute for Stained Glass in Canada has documented the cathedral's windows.

The cathedral holds regular services that allow visitors to experience the interior and artworks firsthand. The central location makes it easy to reach, and guests should check ahead to learn when services and performances are scheduled.

The 43 stained glass windows were made by André Rault and installed in 1951, not by an unnamed craftsman. The Institute for Stained Glass in Canada has documented them. The 1976 fire damaged the Casavant Frères gallery organ of 1930, which was repaired and in 1992–1993 renamed The McGuigan Organ after Sister Marion McGuigan, a local educator and humanitarian.