Palazzo Tosio, Historic palazzo in Brescia, Italy.

Palazzo Tosio is a neoclassical palazzo on Via Tosio in Brescia, rebuilt in three campaigns in the first half of the 19th century on a 16th-century structure. Antonio and Luigi Basiletti worked 1810–1814; Rodolfo Vantini led the transformations of 1824–1829 and 1834–1840. The facade is white Botticino stone, while the arched portico and some ground-floor rooms keep the 16th-century style.

The present palace was rebuilt at least three times in the first half of the 19th century on a 16th-century structure, in neoclassical taste. Antonio and Luigi Basiletti worked between 1810 and 1814; Rodolfo Vantini carried out the radical transformations of 1824-1829 and 1834-1840. The portico arches and some ground-floor rooms keep the 16th-century style.

Palazzo Tosio is now the seat of the Ateneo di Brescia, which holds its meetings in the sala delle adunanze, where paintings by Gabriele Rottini and Luigi Basiletti hang. The Tosio family's private gallery and library once kept works by Raphael and other Italian and foreign artists, together with objects taken from churches or demolished buildings; these passed in 1908 to Palazzo Martinengo da Barco, donated to Brescia by Count Leopardo in 1884, forming the Pinacoteca Tosio Martinengo. Since June 2010 a website has offered a virtual visit of rooms arranged after Count Paolo Tosio's 19th-century plan.

Located on Via Tosio in central Brescia, the palazzo can be explored through virtual tours available on its dedicated website since 2010, offering digital access to its rooms and artworks.

The courtyard fountain with its Naiad by Gaetano Matteo Monti is not the only artwork still in the building: the meeting room of the Ateneo di Brescia keeps paintings by Gabriele Rottini and Luigi Basiletti. The rest of the Tosio collection went to Palazzo Martinengo da Barco in 1908.