San Siro, Roman Catholic church in Genoa, Italy

San Siro is a Catholic church in the Nervi district of Genoa that displays traditional elements of Ligurian ecclesiastical architecture. The building contains spaces for worship and community gatherings organized by the parish.

The church's origins are older than its current building: the first structure dates to the 10th or 11th century, and a chapter of canons is documented by the 13th century. In 1638 the Senate of the Republic of Genoa granted six to seven thousand Genoese lire for rebuilding to a design by the Lombard architect Francesco de Novi. Work ran from 1639 to 1686 or 1689, and Monsignor Agostino Saluzzo consecrated the church on 25 July 1723.

The church keeps the medieval title of pieve (pleban church) and was the seat of a chapter of canons already in the 13th century. Inside are about four thousand relics, donated in 1865 by Giuseppe Sartoria, who had inherited them from his uncle Domenico Gaetano Sartoria, prior of Santa Sabina in Genoa.

The church stands at via Camillo Campostano in Nervi, in eastern Genoa, a short walk from the Nervi seafront. It is an active parish church of the vicariate Nervi-Quinto, so visits fit around Mass times. The single nave with six side altars makes a short circuit; look for the Corvetto tomb, declared a national monument.

The church keeps about four thousand relics, donated in 1865 by Giuseppe Sartoria, who had inherited them from his uncle Domenico Gaetano Sartoria, prior of the church of Santa Sabina in Genoa. The 16th-century panel of Saint Syrus enthroned between Saints Andrew and Bartholomew, by Pier Francesco Sacchi, is now kept in the rectory.