Palacio del Príncipe de Anglona, Baroque palace in Madrid, Spain.

The Palacio del Príncipe de Anglona is a 17th-century palace building occupying the block bounded by Calle Segovia, Calle de San Andrés, Calle de San Pedro and Calle del Príncipe de Anglona, in the Madrid de los Austrias. Built between 1675 and 1690, it was remodelled in the neoclassical taste by Antonio López Aguado between 1802 and 1803. It now holds private flats, with the Instituto Madrileño de Formación on part of the ground floor.

Built between 1675 and 1690, the palace was home to Pedro de Alcántara Téllez-Girón y Pimentel, second Prince of Anglona and son of the ninth Duke of Osuna, before passing to the Dukes of Benavente. Vicente Barcenilla renovated it in 1776, and between 1802 and 1803 Antonio López Aguado adapted it to the neoclassical fashion. Its gardens were redesigned in 1920 by Javier de Winthuysen, and the building was rehabilitated between 1983 and 1986.

The palace takes its name from Pedro de Alcántara Téllez-Girón y Pimentel, second Prince of Anglona and son of the ninth Duke of Osuna, who lived here. The title passed to the Dukes of Benavente. The street now called Calle del Príncipe de Anglona recalls this noble lineage.

The palace occupies a block between Calle Segovia, Calle de San Andrés, Calle de San Pedro and Calle Príncipe de Anglona, in the Madrid de los Austrias. It is a private building: the upper floors are homes and the ground floor houses the Instituto Madrileño de Formación, so there is no visitor entrance. The exterior and the surrounding streets can be seen on foot at any time.

The palace's gardens were reworked in 1920 by the landscape gardener Javier de Winthuysen, who gave them their present layout. The building itself was first remodelled in 1776 by Vicente Barcenilla, and between 1802 and 1803 Antonio López Aguado adapted it to the neoclassical taste of the period. Since the 1983–1986 rehabilitation it has held private flats, with the Instituto Madrileño de Formación on one of the ground floors.