Osaka Prefectural Police, Prefectural police headquarters in Osaka, Japan

Osaka Prefectural Police is the police organization established under Article 36 of Japan's Police Law to cover Osaka Prefecture. Its headquarters, completed in 2008 and designed by Kisho Kurokawa with Osaka Castle in mind, has a wide curved recess of dark grid-patterned glass between two pale towers. It oversees 66 police stations and about 21,474 officers.

The force traces its origins to the 1868 Rōkata corps and the 1874 police section of the prefectural office. In 1948 the old Police Law split it into the National Rural Police and the Osaka City Metropolitan Police; the 1954 Police Law, effective 1 July 1954, reunited them as the Osaka Prefectural Police, which absorbed the Osaka City Police on 1 July 1955. The present headquarters, designed by Kisho Kurokawa with Osaka Castle in mind, was completed in 2008.

The department implements a community-based policing model that integrates local citizens through Public Safety Commissions for operational oversight.

The main headquarters is located in central Osaka and is open to the public for administrative matters. Visitors can contact any station throughout the prefecture for emergencies, as they operate around the clock.

The headquarters building, completed in 2008, was designed by Kisho Kurokawa with Osaka Castle in mind; its curved central glass recess and flanking pale towers echo the castle's form. The force began dedicated "mie-tari" spot-search teams in 1978, the first in Japan.