Cathedral of Loja-Parroquia El Sagrario, Catholic cathedral in Loja, Ecuador.

The Cathedral of Loja displays a Republican-style facade with meeting halls and crypts in its rear section connected to the cathedral chapter. The building unifies these spaces into a coherent structure serving both religious and administrative purposes.

In 1566 Juan Salinas de Loyola and Alonso de Mercadillo chose the site for a church of stone and adobe, but that first construction collapsed. In 1749 General Pedro Javier Valdivieso directed a new building. The church was consecrated as the Cathedral of Loja on 31 October 1895 by Monseñor José María Riofrío.

The cathedral is the seat of the Diocese of Loja and its parish is El Sagrario. Its eclectic style mixes historicist, neoclassical and Corinthian elements, and the facade has four sections topped by a tower and bell tower. The name El Sagrario refers to the parish dedicated to keeping the Blessed Sacrament.

The cathedral faces Loja's Parque Central, about 70 km from the Santuario de Nuestra Señora de El Cisne. The main entrance opens onto the square; the four-body facade ends in a tower and bell tower. The marble floor and gilded wooden altar installed in 2004 are inside. As an active diocesan seat, visits may coincide with services.

The 2004 renovation replaced the wooden floor with marble and installed a new gilded wooden altar; the baldachin was moved into one of the side aisles. The facade had already been renewed in 1944, and a full restoration backed by the Central Bank of Ecuador ran from 1988 to 1990, when many murals were repainted.