Metropolitan Cathedral of Saint Sebastian, Colonial cathedral in Cercado, Bolivia.

The Metropolitan Cathedral of Saint Sebastian is a church on the main square of Cochabamba, in Bolivia's Cercado district, built in Spanish baroque style using stone and adobe masonry. The facade features detailed stonework and decorative tilework that are characteristic of this architectural tradition.

The first church on the site was begun in 1571, built on the foundations of the 14th-century Villa de Oropeza. In 1618 the administrators agreed to build a larger church to replace the deteriorating one and serve a growing population. The present building was raised in 1701 on the earlier foundations and finished in 1735; it became a National Heritage Site in September 2012.

The cathedral is dedicated to Saint Sebastian, and the archbishop's formal possession of the see is held here, the most representative liturgical act in the department. The facade's salomonic columns, low round arches and wide ogee rose window were first noted by the researcher E. Wethey, who studied Cochabamba's viceregal monuments.

The cathedral stands on Plaza 14 de Septiembre, the city's central square, so it is easy to locate and reach on foot from most parts of the city center. Visiting on a weekday outside of main service times is likely to give a quieter experience inside.

The 1571 church was raised on the foundations of the 14th-century Villa de Oropeza, so the colonial building stands on a medieval settlement layer, not a 16th-century one. The 1701 replacement kept that base. The cathedral was declared a National Heritage Site by the Senate of Bolivia in September 2012.